NEETZoologyChemical Coordination and Integration
Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Glucagon is considered a hyperglycemic hormone. Reason (R): Glucagon acts mainly on hepatocytes to stimulate glycogenolysis and gluconeogenesis, while reducing cellular glucose uptake and utilisation. In the light of the above statements, choose the most appropriate answer from the options given be
Options
- ABoth Assertion (A) and Reason (R) are true but Reason (R) is not the correct explanation of Assertion (A).
- BBoth Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of Assertion (A).
- CAssertion (A) is true but Reason (R) is false.
- DAssertion (A) is false but Reason (R) is true.
Correct answer
B. Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of Assertion (A).
Step-by-step solution
Assertion (A) is true because glucagon increases the blood glucose level, which is termed hyperglycemia. Reason (R) is also true and provides the exact physiological mechanism for the Assertion. According to NCERT, glucagon is a peptide hormone that acts mainly on the liver cells (hepatocytes). It stimulates glycogenolysis and gluconeogenesis, both of which add glucose to the blood. Furthermore, it reduces cellular glucose uptake and utilisation, preventing glucose from leaving the bloodstream. Together, these acti