Given below are five events related to blood coagulation and formed elements. (A) Conversion of inactive fibrinogens to fibrins (B) Formation of the enzyme complex thrombokinase (C) Trapping of dead formed elements which are normally destroyed in the spleen (D) Conversion of prothrombin to thrombin (E) Release of certain factors by injured tissues and platelets Choose the correct sequential order of these events from

Step-by-step solution

The mechanism of blood coagulation proceeds in a specific cascade: First, an injury stimulates platelets and tissues at the site to release certain factors (E). These factors initiate a cascade of enzymic reactions leading to the formation of the enzyme complex thrombokinase (B). Thrombokinase then catalyzes the conversion of inactive prothrombin in the plasma into the active enzyme thrombin (D). Thrombin, in turn, converts inactive fibrinogens into fibrins (A). Finally, fibrins form a network of threads that trap