NEETZoologyBody Fluids and Circulation
A patient requires a blood transfusion. His parents have blood groups A and B, and his biological sister has blood group O. Blood tests reveal that the patient's plasma contains neither anti-A nor anti-B antibodies. What is the patient's genotype and which blood groups can he safely receive?
Options
- Aii ; O only
- BI^A I^B ; AB only
- CI^A I^B ; A, B, AB and O
- DI^A i ; A and O
Correct answer
C. I^A I^B ; A, B, AB and O
Step-by-step solution
The patient's sister has blood group O (genotype ii ), which means both parents must carry the recessive i allele. Since the parents have blood groups A and B, their genotypes must be I^A i and I^B i , respectively. The patient's blood plasma contains neither anti-A nor anti-B antibodies. According to the principles of blood groups, the absence of both these antibodies in the plasma is a characteristic of blood group AB. Therefore, the patient's genotype must be I^A I^B . Individuals with blood group AB have both A