Which of the following substances, if introduce in the blood stream, would cause coagulation, at the site of its introduction?

Step-by-step solution

Lipoproteinaceous, thromboplastin is released by the injured tissue. This reacts with Ca ²⁺ ions present in blood and forms a proteinaceous enzyme called prothrombinase. Later in the presence of Ca ²⁺ inactivates heparin (anticoagulant) and catalyses prothrombin (inactive plasma protein) into an active thrombin protein. Thrombin acts as an enzyme and catalyses fibrinogen (a soluble plasma protein) into an insoluble fibre like polymer, fibrin. These fibres form a dense network upon the wound and trap blood corpuscle