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NEET
Exam
NEET
Subject
Zoology
Chapter
Excretory Products and their Elimination

NEET · Zoology · Excretory Products and their Elimination

What hormone is released by the JGA cells in response to a fall in...

What hormone is released by the JGA cells in response to a fall in GFR?

Options

  1. AAtrial Natriuretic Factor (ANF)
  2. BAldosterone
  3. CRenin
  4. DAngiotensin II

Correct answer

C. Renin

Step-by-step solution

The JGA plays a complex regulatory role. A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release renin which converts angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR. Angiotensin II also activates the adrenal cortex to release Aldosterone. Aldosterone causes reabsorption of Na⁺ and water from the distal parts of the tubule. This also leads to an increase in blood pressure and GFR. This complex mechanism is generally known as the Renin-Angiotensin mechanism.

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