A fall in the Glomerular Filtration Rate (GFR) activates specific modified cells in the Juxtaglomerular Apparatus (JGA) to release renin. These secretory cells are formed by the cellular modifications of the:

Step-by-step solution

The Juxtaglomerular Apparatus (JGA) is a specialized region formed at the contact point between the distal convoluted tubule (DCT) and the afferent arteriole of the same nephron. At this location, the cells of the afferent arteriole undergo cellular modifications to form the Juxtaglomerular (JG) cells. When there is a fall in the Glomerular Filtration Rate (GFR), these JG cells are activated to secrete the enzyme renin, which helps in restoring the GFR. The cells of the DCT are modified to form the macula densa, no