Given below are key events occurring during the human menstrual cycle: A. Secretion of high levels of estrogens by growing follicles B. Rapid secretion of LH leading to its maximum level (LH surge) C. Rupture of the Graafian follicle and release of the ovum D. Transformation of the ruptured follicle into the corpus luteum E. Secretion of large amounts of progesterone Choose the correct chronological sequence of these

Step-by-step solution

During the follicular phase of the menstrual cycle, the growing follicles secrete increasing amounts of estrogens (A). High levels of estrogens eventually trigger a rapid secretion of LH from the anterior pituitary, known as the LH surge (B). This LH surge directly induces the rupture of the mature Graafian follicle, causing the release of the ovum, which is ovulation (C). Following ovulation, the remaining parts of the ruptured follicle transform into a glandular structure called the corpus luteum (D). The newly f