Arrange the sequence of hormonal and ovarian events during the pre-ovulatory phase of the menstrual cycle. (A) Rapid secretion of LH leading to LH surge (B) GnRH stimulates release of gonadotropins (C) Rupture of Graafian follicle (D) Secretion of estrogens by the growing follicles (E) Gonadotropins stimulate follicular development Choose the correct answer from the options given below:

Step-by-step solution

The correct chronological sequence of events during the pre-ovulatory (follicular) phase is: First, Gonadotropin releasing hormone (GnRH) from the hypothalamus stimulates the anterior pituitary to release gonadotropins (LH and FSH) (Statement B). Second, the increased levels of gonadotropins stimulate follicular development in the ovary (Statement E). Third, as the follicles grow, they secrete increasing amounts of estrogens (Statement D). Fourth, the high levels of estrogens eventually trigger a rapid secretion of