During the secretory phase of the menstrual cycle, the secretion of gonadotropins (FSH and LH) is significantly suppressed, preventing the recruitment of new ovarian follicles. The elevated level of which of the following hormones is primarily responsible for this negative feedback?

Step-by-step solution

The secretory phase (also known as the luteal phase) of the menstrual cycle is characterized by the formation of the corpus luteum from the ruptured Graafian follicle. The corpus luteum secretes large amounts of progesterone, which is essential for the maintenance of the endometrium. These high levels of progesterone exert a strong negative feedback effect on the hypothalamus and the anterior pituitary gland. This negative feedback suppresses the release of gonadotropins (FSH and LH), thereby preventing the develop