NEETZoologyMolecular Basis of Inheritance
Which of the following was not considered as a possible candidate for the transforming principle?
Options
- AProteins
- BRNA
- CDNA
- DLipids
Correct answer
D. Lipids
Step-by-step solution
Prior to the work of Oswald Avery, Colin MacLeod and Maclyn McCarty (1933-44), the genetic material was thought to be a protein. They worked to determine the biochemical nature of ‘transforming principle’ in Griffith's experiment. They purified biochemicals (proteins, DNA, RNA, etc.) from the heat-killed S cells to see which ones could transform live R cells into S cells. They discovered that DNA alone from S bacteria caused R bacteria to become transformed. They also discovered that protein-digesting enzymes (prot