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Molecular Basis of Inheritance — NEET UG Zoology PYQs

910 previous year questions from Molecular Basis of Inheritance with answers and solutions. Numbered list, year tags, and one-tap solutions — built for serious JEE / NEET practice.

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1

Which of the following statements about lac-operon is correct ?

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2

Which of the following enzymes synthesizes precursor mRNA ?

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3

Which of the following statements are correct with reference to a transcription unit ? A. A transcription unit in DNA is defined primarily by three regions : promoter, structural g

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4

Which of the following statements are correct with reference to packaging of DNA helix ? A. Histones are organized to form a unit of eight molecules called histone octamer. B. Hist

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5

Arrange the following steps of DNA fingerprinting in a correct sequence. A. Isolation of DNA and its digestion by restriction endonucleases. B. Hybridisation using a labelled VNTR

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6

In the lac operon, the z gene codes for :

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7

Given below are two statements : Statement I : In the RNA world, RNA is considered the first genetic material evolved to carry out essential life processes. RNA acts as a genetic m

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8

Match List I with List II: array |l|l|l|l| & List - I & & List - II A . & Alfred Hershey and Martha Chase & (i) & Streptococcus pneumoniae B. & Euchromatin & (ii) & Densely packed

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9

Which of the following are the post-transcriptional events in an eukaryotic cell? A. Transport of pre-mRNA to cytoplasm prior to splicing. B. Removal of introns and joining of exon

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10

Which factor is important for termination of transcription?

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11

Histones are enriched with -

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12

Which chromosome in the human genome has the highest number of genes?

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13

Who proposed that the genetic code for amino acids should be made up of three nucleotides?

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14

In a chromosome, there is a specific DNA sequence, responsible for initiating replication. It is called as:

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15

Given below are two statements regarding RNA polymerase in prokaryotes. Statement I : In prokaryotes, RNA polymerase is capable of catalysing the process of elongation during trans

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16

Match List-I with List-II: array |l|l|r|l| & List-I & & List-II A. & Histones & I. & Loosely packed chromatin B. & Nucleosome & II. & Densely packed Chromatin C. & Euchromatin & II

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17

Given below are two statements : Statement I: In the lac operon, the z gene codes for beta-galactosidase which is primarily responsible for the hydrolysis of lactose into galactose

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18

A transcription unit in DNA is defined primarily by the three regions in DNA and these are with respect to upstream and down stream end;

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19

The lactose present in the growth medium of bacteria is transported to the cell by the action of

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20

Match List I with List II Choose the correct answer from the options given below:

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21

Which of the following statement is correct regarding the process of replication in E.coli?

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22

Which one is the correct product of DNA dependent RNA polymerase to the given template? 3'TACATGGCAAATATCCATTCA5

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23

Match List I with List II: array |l|l|r|l| & List I & & List II A. & RNA polymerase III & I. & snRNPs B. & array l Termination of transcription array & II. & Promotor C. & Splicing

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24

Given below are two statements: Statement I: In eukaryotes there are three RNA polymerases in the nucleus in addition to the RNA polymerase found in the organelles. Statement II: A

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25

Name the component that binds to the operator region of an operon and prevents RNA polymerase from transcribing the operon.

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26

The last chromosome sequenced in Human Genome Project was :

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27

Given below are two statements : Statement I: The process of copying genetic information from one strand of the DNA into RNA is termed as transcription. Statement II : A transcript

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28

Which scientist conducted an experiment with ³² P and ³⁵ ~S labelled phages for demonstrating that DNA is the genetic material?

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29

Given below are two statements: Statement I: RNA being unstable, mutate at a faster rate. Statement II: RNA can directly code for synthesis of proteins, hence can easily express th

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30

With reference to Hershey and Chase experiments. Select the correct statements. (A) Viruses grown in the presence of radioactive phosphorus contained radioactive DNA. (B) Viruses g

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31

Which one of the following acts as an inducer for lac operon?

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32

Expressed Sequence Tags (ESTs) refers to

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33

Given below are two statements: Statement I: In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid. Statement II: In

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34

Unequivocal proof that DNA is the genetic material was first proposed by

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35

The salient features of genetic code are : (A) The code is palindromic (B) UGA act as initiator codon (C) The code is unambiguous and specific (D) The code is nearly universal Choo

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36

What is the role of RNA polymerase III in the process of transcription in Eukaryotes?

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37

Match List I with List II: List I List II A. Gene 'a' I. Beta-galactosidase B. Gene 'y' II. Transacetylase C. Gene 'i' III. Permease D. Gene 'z' IV.

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38

Which of the following is the sequence on corresponding coding strand, if the sequence on mRNA formed is as follows 5' AUCGAUCGAUCGAUCGAUCGAUCGAUCG '3

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39

Given below are two statements: Statement I: RNA mutates at a faster rate. Statement II: Viruses having RNA genome and shorter life span mutate and evolve faster. In the light of t

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40

In lac operon, z gene codes for :

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41

Given below are two statements : Statement I : DNA polymerases catalyse polymerisation only in one direction, that is 5^ 3^ Statement II : During replication of DNA, on one strand

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42

Match List - I with List - II : Choose the correct answer from the options given below :

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43

If DNA contained sulphur instead of phosphorus and proteins contained phosphorus instead of sulfur, what would have been the outcome of Hershey and Chase experiment?

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44

If A and C make 30 % and 20 % of DNA, respectively, what will be the percentage composition of T and G ?

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45

The process of translation of mRNA to proteins begins as soon as :

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46

Read the following statements and choose the set of correct statements: (a) Euchromatin is loosely packed chromatin. (b) Heterochromatin is transcriptionally active. (c) Histone oc

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47

DNA Polymorphism forms the basis of:

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48

If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different segments, the methodology adopted by him is

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49

In an E. coli strain, i gene gets mutated, and its product cannot bind the inducer molecule. If the growth medium is provided with lactose, what will be the outcome?

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50

If the length of a DNA molecule is 1 . 1 metres, what will be the approximate number of base pairs?

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51

Ten E. coli cells with N 15 -dsDNA are incubated in medium containing N 14 nucleotide. After 60 minutes, how many E. coli cells will have DNA totally free from N 15 ?

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52

Match List-I with List-II : ( array |l|l| List - I & List - II (a) Bacteriophage 174 & (i) 48502 base pairs (b) Bacteriophage lambda & (ii) 5386 nucleotides (c) Escherichia coli &

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53

Against the codon 5' UAC 3', what would be the sequence of anticodon on tRNA ?

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54

Complete the flow chart on central dogma.

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55

Identify the correct statement.

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56

What is the role of RNA polymerase III in the process of transcription in eukaryotes?

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57

DNA fingerprinting involves identifying differences in some specific regions in DNA sequence, called as:

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58

If Adenine makes 30 % of the DNA molecule, what will be the percentage of Thymine, Guanine and Cytosine in it?

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59

Which of the following RNAs is not required for the synthesis of protein?

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60

Which is the "Only enzyme" that has "Capability" to catalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes?

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61

Which one of the following statements about histones is wrong?

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62

Statement I: The codon 'AUG' codes for methionine and phenylalanine. Statement II: 'AAA' and 'AAG' both codons code for the amino acid lysine. In the light

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63

The term 'Nuclein' for the genetic material was used by:

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64

In the polynucleotide chain of DNA , a nitrogenous base is linked to the - OH of:

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65

E. coli has only 4 . 6 × 10 6 base pairs and completes the process of replication within 18 minutes; then the average rate of polymerisation is approximately:

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66

Which is the basis of genetic mapping of human genome as well as DNA fingerprinting?

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67

Name the enzyme that facilitates opening of DNA helix during transcription.

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68

Which of the following statements is correct?

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69

The first phase of translation is

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70

If the distance between two consecutive base pairs is 0 . 34   nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is 6 . 6 × 10 9 bp

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71

Who discovered DNA fingerprinting?

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72

Which of the following switches off lac operon?

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73

The group of codons which codes for alanine is

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74

Assertion : In eukaryotes, both intron and exon are transcribed to form hnRNA. Reason : Splicing is required in prokaryotes.

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75

Identify A, B and C.

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76

Chromosome walking is

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77

RNA binds to tRNA through

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78

In DNA 20 % bases are adenine. What percentage of bases are pyrimidines?

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79

Which of the following is not a stop codon?

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80

During DNA replication, supercoilling is relaxed by

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81

Which of the following is not true?

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82

From the following, identify the correct combination of salient features of Genetic code.

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83

Match the following RNA polymerases with their transcribed products Select the correct option from the following

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84

"Ramachandran plot" is used to confirm the structure of

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85

Purines found both in DNA and RNA are

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86

Expressed sequence tags (ESTs) refers to:

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87

Which of the following features of genetic code does allow bacteria to produce human insulin by recombinant DNA technology?

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88

Match the following genes of the Lac operon with their respective products: Column-I Column-II a   i gene   i ß-galactosidase b z gene i i Permease c a gene i i i R

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89

What will be the sequence of mRNA produced by the following stretch of DNA? 3'ATGCATGCATGCATG5' TEMPLATE STRAND 5'TACGTACGTACGTAC3' CODING STRAND

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90

Which scientist experimentally proved that DNA is the sole genetic material in bacteriophage?

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91

What initiation and termination factors are involved in transcription in eukaryotes?

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92

In the process of transcription in eukaryotes, the RNA polymerase I transcribes

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93

Under which of the following conditions will there be no change in the reading frame of the following mRNA? 5'AACAGCGGUGCUAUU 3'

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94

Assertion: Amber codon is a termination codon. Reason : If in m RNA, a termination codon is present, the protein synthesis stops abruptly whether the protein synthesis is completed

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95

Which of the following is a non-sense mutation?

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96

Find out the incorrect match.

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97

Codons of alanine are

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98

Which of the following statements is correct regarding eukaryotic translation?

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99

To which of the following, repressor protein is attached?

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100

Which of the following mRNA can be transcripted as

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101

Which is present at 5^ end of eukaryotic mRNA?

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102

Linker-DNA is attached to

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103

Select the correct match:

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104

The experimental proof for semiconservative replication of DNA was first shown in a

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105

All of the following are part of an operon except

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106

AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?

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107

Select the correct match:

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108

Match the triplet codons listed in column I with their amino acids mentioned in column II and select the correct option from the given codes.

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109

Refer to the given figure and select the correct option regarding its parts labelled as A, B and C .

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110

Minisatellites or VNTR’s are used in

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111

hnRNA undergoes two additional process. Out of them in one process an unusual nucleotide (methyl GPT) is added to the 5 ' end of molecule. What would you called this?

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112

In the lac operon model, lactose molecules function as

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113

If there are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many

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114

The association of histone H 1 with a nucleosome indicates:

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115

Which of the following statements is correct? a. rRNA is the most abundant RNA. b. Ribosomes are composed of approximately 80% rRNA and 20% ribosomal proteins. c. rRNA is a type of

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116

During DNA replication, Okazaki fragments are used to elongate:

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117

The final proof for DNA as the genetic material came from the experiments of

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118

Spliceosomes are not found in cells of:

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119

In a 3.2 Kbp long piece of DNA, 820 adenine bases were found. What would be the number of cytosine bases?

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120

If the sequence of bases in the coding strand of a double stranded DNA is 5'-GTTCGAGTC-3', the sequence of bases in its transcript will be

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