NEETZoologyMolecular Basis of Inheritance
What is a classical example of point mutation?
Options
- ADeletion of a large segment of DNA
- BRearrangement of a segment of DNA
- CInsertion of a large segment of DNA
- DChange of a single base pair in a gene
Correct answer
D. Change of a single base pair in a gene
Step-by-step solution
The relationships between genes and DNA are best understood by mutation studies. You have studied about mutation and its effect in Chapter 4. Effects of large deletions and rearrangements in a segment of DNA are easy to comprehend. It may result in loss or gain of a gene and so a function. The effect of point mutations will be explained here. A classical example of point mutation is a change of single base pair in the gene for beta globin chain that results in the change of amino acid residue glutamate to valine. I