NEETZoologyMolecular Basis of Inheritance
What is the effect of insertion or deletion of one or two bases in DNA?
Options
- AIt results in frameshift mutations
- BIt changes the reading frame from the point of insertion or deletion
- CIt changes one or multiple amino acids
- DIt results in the change of amino acid residue
Correct answer
A. It results in frameshift mutations
Step-by-step solution
A classical example of point mutation is a change of single base pair in the gene for beta globin chain that results in the change of amino acid residue glutamate to valine. It results in a diseased condition called sickle cell anemia. Effect of point mutations that inserts or deletes a base in structural genes can be better understood by following simple examples. Insertion or deletion of one or two bases changes the reading frame from the point of insertion or deletion. However, such mutations are referred to as