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NEETZoologyMolecular Basis of Inheritance

What are the polymorphic DNA sequences used to generate genetic and physical maps of the genome?

Options

  1. AMicrosatellites
  2. BESTs
  3. CSequence tags
  4. DRestriction endonuclease recognition sites

Correct answer

A. Microsatellites

Step-by-step solution

The sequence of chromosome 1 was completed only in May 2006 (this was the last of the 24 human chromosomes – 22 autosomes and X and Y – to be sequenced. Another challenging task was assigning the genetic and physical maps on the genome. This was generated using information on polymorphism of restriction endonuclease recognition sites, and some repetitive DNA sequences known as microsatellites (one of the applications of polymorphism in repetitive DNA sequences shall be explained in next section of DNA fingerprintin

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