NEETZoologyMolecular Basis of Inheritance
Select the incorrect statement for the given figure.
Options
- AThe technique of DNA Fingerprinting was initially developed by Alec Jeffreys and he used a satellite DNA as a
- BThe technique as used earlier, involved Northern blot hybridisation using radiolabeled VNTR as a probe.
- CThe VNTR belongs to a class of satellite DNA referred to as mini-satellite.
- DThe numbers of repeats show a very high degree of polymorphism, as a result the size of VNTR varies in size fr
Correct answer
B. The technique as used earlier, involved Northern blot hybridisation using radiolabeled VNTR as a probe.
Step-by-step solution
The technique of DNA Fingerprinting was initially developed by Alec Jeffreys. He used a satellite DNA as a probe that showed a very high degree of polymorphism. It was called the Variable Number of Tandem Repeats (VNTR). The technique, as used earlier, involved Southern blot hybridisation using radiolabeled VNTR as a probe. The VNTR belongs to a class of satellite DNA referred to as mini-satellite. A small DNA sequence is arranged tandemly in many copy numbers. The copy number varies from chromosome to chromosome i