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NEETZoologyMolecular Basis of Inheritance

Match List-I with List-II regarding the packaging of DNA helix. List-I List-II (A) DNA (I) Lysine and Arginine (B) Histone octamer (II) Negatively charged polymer (C) Basic amino acids (III) Required for higher level packaging (D) NHC proteins (IV) Positively charged core Choose the correct answer from the options given below:

Options

  1. A(A)-(IV), (B)-(II), (C)-(I), (D)-(III)
  2. B(A)-(II), (B)-(IV), (C)-(I), (D)-(III)
  3. C(A)-(II), (B)-(IV), (C)-(III), (D)-(I)
  4. D(A)-(I), (B)-(III), (C)-(IV), (D)-(II)

Correct answer

B. (A)-(II), (B)-(IV), (C)-(I), (D)-(III)

Step-by-step solution

DNA is a negatively charged polymer due to the presence of phosphate groups. Histones are organized to form a unit of eight molecules called a histone octamer, which acts as a positively charged core. Histones acquire their positive charge because they are rich in the basic amino acid residues lysine and arginine. The packaging of chromatin at higher levels requires an additional set of proteins collectively referred to as Non-Histone Chromosomal (NHC) proteins. Therefore, the correct matching is (A)-(II), (B)-(IV)

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