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NEETZoologyMolecular Basis of Inheritance

For an inheritable mutation to be classified as a DNA polymorphism in a human population, the variant allele must occur at a locus with a frequency:

Options

  1. AGreater than 0.1
  2. BGreater than 0.01
  3. CExactly 0.01
  4. DGreater than 0.001

Correct answer

B. Greater than 0.01

Step-by-step solution

According to NCERT, allelic sequence variation has traditionally been described as a DNA polymorphism if more than one variant (allele) at a locus occurs in human population with a frequency greater than 0.01 . If an inheritable mutation is observed in a population at this high frequency, it is referred to as DNA polymorphism. Frequencies like 0.1 or 0.001 are incorrect due to decimal shift errors, and the condition strictly requires the frequency to be 'greater than' 0.01 , making 'exactly 0.01 ' incorrect. Answer

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