An mRNA molecule has the following nucleotide sequence: 5^ -CGA UAC GGU UAA- 3^ What will be the sequence and polarity of the DNA coding strand from which this mRNA was transcribed?

Step-by-step solution

The coding strand of DNA has the same sequence and polarity ( 5^ 3^ ) as the transcribed mRNA, with the only difference being that DNA contains thymine (T) in place of uracil (U). Given mRNA sequence: 5^ -CGA UAC GGU UAA- 3^ Replacing uracil (U) with thymine (T) while maintaining the 5^ 3^ polarity gives the coding strand sequence: 5^ -CGA TAC GGT TAA- 3^ . The sequence 3^ -GCT ATG CCA ATT- 5^ represents the template strand, which is complementary and antiparallel to the mRNA. Answer: 5^ -CGA TAC GGT TAA- 3^