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NEETZoologyMolecular Basis of Inheritance

Match List I with List II regarding the packaging of DNA helix. List I List II (A) Positively charged amino acids (I) Nucleosome (B) Negatively charged molecule (II) H1 protein (C) Linker histone (III) DNA (D) Repeating unit of chromatin (IV) Lysine and Arginine Choose the correct answer from the options given below:

Options

  1. A(A) - (IV), (B) - (III), (C) - (II), (D) - (I)
  2. B(A) - (IV), (B) - (III), (C) - (I), (D) - (II)
  3. C(A) - (III), (B) - (IV), (C) - (II), (D) - (I)
  4. D(A) - (I), (B) - (II), (C) - (III), (D) - (IV)

Correct answer

A. (A) - (IV), (B) - (III), (C) - (II), (D) - (I)

Step-by-step solution

Histones are basic proteins that are rich in positively charged basic amino acid residues, namely Lysine and Arginine. DNA is an acidic molecule and carries a net negative charge due to its phosphate groups. The linker histone that binds to the DNA between nucleosomes is the H1 protein. The repeating unit of chromatin, which appears as 'beads-on-string' under an electron microscope, is the nucleosome. Therefore, the correct match is (A)-(IV), (B)-(III), (C)-(II), (D)-(I). Answer: (A) - (IV), (B) - (III), (C) - (II)

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