NEETZoologyMolecular Basis of Inheritance
Consider the following double-stranded DNA sequence of a transcription unit: Strand I: 5' - A T G C A T G - 3' Strand II: 3' - T A C G T A C - 5' If the promoter is located towards the 5' end of Strand I, what will be the sequence of the transcribed mRNA?
Options
- A5' - C A U G C A U - 3'
- B3' - U A C G U A C - 5'
- C5' - A T G C A T G - 3'
- D5' - A U G C A U G - 3'
Correct answer
D. 5' - A U G C A U G - 3'
Step-by-step solution
According to the conventions for defining a transcription unit, the promoter is located towards the 5' end of the coding strand. Since the promoter is located at the 5' end of Strand I, Strand I is the coding strand and Strand II is the template strand. The mRNA is transcribed from the template strand (Strand II) and has a sequence complementary to it, which makes it identical to the coding strand (Strand I), except that thymine (T) is replaced by uracil (U). Coding strand (Strand I): 5' - A T G C A T G - 3' Transc