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NEETZoologyMolecular Basis of Inheritance

Consider the following double-stranded DNA sequence of a transcription unit: Strand I: 5' - A T G C A T G - 3' Strand II: 3' - T A C G T A C - 5' If the promoter is located towards the 5' end of Strand I, what will be the sequence of the transcribed mRNA?

Options

  1. A5' - C A U G C A U - 3'
  2. B3' - U A C G U A C - 5'
  3. C5' - A T G C A T G - 3'
  4. D5' - A U G C A U G - 3'

Correct answer

D. 5' - A U G C A U G - 3'

Step-by-step solution

According to the conventions for defining a transcription unit, the promoter is located towards the 5' end of the coding strand. Since the promoter is located at the 5' end of Strand I, Strand I is the coding strand and Strand II is the template strand. The mRNA is transcribed from the template strand (Strand II) and has a sequence complementary to it, which makes it identical to the coding strand (Strand I), except that thymine (T) is replaced by uracil (U). Coding strand (Strand I): 5' - A T G C A T G - 3' Transc

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