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NEETZoologyMolecular Basis of Inheritance

Match List-I with List-II regarding the methodologies and tools of the Human Genome Project. List-I List-II (A) Expressed Sequence Tags (I) Principle developed by Frederick Sanger (B) Sequence Annotation (II) Cloning vectors for amplification (C) BAC and YAC (III) Identifying all genes expressed as RNA (D) Automated DNA sequencer (IV) Blind approach for sequencing whole genome Choose the correct answer from the optio

Options

  1. A(A)-(IV), (B)-(III), (C)-(II), (D)-(I)
  2. B(A)-(III), (B)-(IV), (C)-(I), (D)-(II)
  3. C(A)-(IV), (B)-(III), (C)-(I), (D)-(II)
  4. D(A)-(III), (B)-(IV), (C)-(II), (D)-(I)

Correct answer

D. (A)-(III), (B)-(IV), (C)-(II), (D)-(I)

Step-by-step solution

Expressed Sequence Tags (ESTs) is a methodology that focuses on identifying all the genes that are expressed as RNA. Sequence Annotation is a blind approach of simply sequencing the whole set of genome that contains all the coding and non-coding sequences, and later assigning different regions in the sequence with functions. BAC (Bacterial Artificial Chromosomes) and YAC (Yeast Artificial Chromosomes) are specialized vectors used for cloning and amplifying the DNA fragments in suitable hosts. Automated DNA sequence

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