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NEETZoologyMolecular Basis of Inheritance

In a hypothetical transcription unit, the coding strand of DNA has the following sequence: 5' -TACGTAGC- 3' What will be the sequence of the transcribed mRNA, and at which end of this coding strand is the terminator located?

Options

  1. AmRNA: 5' -UACGUAGC- 3' ; Terminator: 5' end
  2. BmRNA: 5' -UACGUAGC- 3' ; Terminator: 3' end
  3. CmRNA: 3' -AUGCAUCG- 5' ; Terminator: 3' end
  4. DmRNA: 5' -TACGTAGC- 3' ; Terminator: 3' end

Correct answer

B. mRNA: 5' -UACGUAGC- 3' ; Terminator: 3' end

Step-by-step solution

By convention, the sequence of the transcribed mRNA is identical to the coding strand of DNA, with the only exception being that Thymine (T) is replaced by Uracil (U) in RNA. Given coding strand: 5' -TACGTAGC- 3' Transcribed mRNA: 5' -UACGUAGC- 3' Furthermore, all reference points while defining a transcription unit are made with respect to the coding strand. The terminator is located towards the 3' end (downstream) of the coding strand, which defines the end of the transcription process. Answer: mRNA: 5' -UACGUAGC

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