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NEETZoologyMolecular Basis of Inheritance

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): In the Human Genome Project, the Expressed Sequence Tags (ESTs) approach involves sequencing only a fraction of the total genome rather than the entire DNA sequence. Reason (R): The EST approach focuses exclusively on identifying all the genes that are expressed as RNA. In the light of the above st

Options

  1. ABoth Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of Assertion (A)
  2. BBoth Assertion (A) and Reason (R) are true but Reason (R) is not the correct explanation of Assertion (A)
  3. CAssertion (A) is true but Reason (R) is false
  4. DAssertion (A) is false but Reason (R) is true

Correct answer

A. Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of Assertion (A)

Step-by-step solution

The Human Genome Project utilized two major methodologies. One approach, called Expressed Sequence Tags (ESTs), focused solely on identifying all the genes that are expressed as RNA. Because this method specifically targets only the transcriptionally active (expressed) genes, it inherently ignores the vast non-coding and unexpressed regions of the genome, thereby sequencing only a fraction of the total DNA. The other approach, Sequence Annotation, involved sequencing the entire genome (coding and non-coding). There

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