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NEETZoologyMolecular Basis of Inheritance

Match List I with List II regarding the packaging of DNA helix. List I List II A. Histone octamer I. Negatively charged polymer B. DNA II. Positively charged basic proteins C. Nucleosome III. Required for higher level packaging of chromatin D. NHC proteins IV. Structure containing 200 bp of DNA helix Choose the correct answer from the options given below:

Options

  1. AA-I, B-II, C-IV, D-III
  2. BA-II, B-I, C-III, D-IV
  3. CA-II, B-I, C-IV, D-III
  4. DA-III, B-I, C-IV, D-II

Correct answer

C. A-II, B-I, C-IV, D-III

Step-by-step solution

Histones are positively charged, basic proteins that are organised to form a unit of eight molecules called histone octamer. DNA is a negatively charged polymer due to the presence of phosphate groups. The negatively charged DNA is wrapped around the positively charged histone octamer to form a nucleosome. A typical nucleosome contains 200 bp of DNA helix. The packaging of chromatin at a higher level requires an additional set of proteins collectively referred to as Non-histone chromosomal (NHC) proteins. Therefore

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