NEET2001ZoologyMolecular Basis of InheritanceActual
Assertion : Watson and Crick provided experimental proof of semiconservative nature of DNA relication. Reason : DNA polymerase binds nucleotides in replication.
Options
- AIf both Assertion and Reason are true and Reason is the correct explantion of Assertion
- BIf both Assertion and Reason are true and Reason is not the correct explanation of Assertion
- CIf Assertion is true but Reason is false
- DIf Assertion is false but Reason is true.
Correct answer
D. If Assertion is false but Reason is true.
Step-by-step solution
Watson and Crick suggested the double helical structure of DNA. Semiconservative nature of DNA replication was proved by Messelson and Stahl by using heavy isotope of nitrogen ( ¹⁵ ~N ) . DNA polymerase III establishes phosphodiester linkages between the adjacent deoxyribo-nucleoside phosphate in presence of ATP/GTP, TPP and Mg ²⁺ . It produces a new strand of DNA. DNA polymerase binds nucleotides in 5'-3' direction.