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NEETZoologyPrinciples of Inheritance and Variation

What is the likelihood of a heterozygous individual being affected by sickle-cell anaemia?

Options

  1. A100 percent
  2. B50 percent
  3. C25 percent
  4. D0 percent

Correct answer

D. 0 percent

Step-by-step solution

This is an autosome linked recessive trait that can be transmitted from parents to the offspring when both the partners are carrier for the gene (or heterozygous). The disease is controlled by a single pair of allele, HbA and HbS . Out of the three possible genotypes only homozygous individuals for HbS (HbSHbS ) show the diseased phenotype . Heterozygous (HbAHbS ) individuals appear apparently unaffected but they are carrier of the disease as there is 50 per cent probability of transmission of the mutant gene to th

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