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NEETZoologyPrinciples of Inheritance and Variation

Why is it extremely rare for a female to be haemophilic?

Options

  1. ABecause the gene is dominant in females
  2. BBecause both parents must be carriers for the female to be affected
  3. CBecause the female would need to inherit two mutated X chromosomes
  4. DBecause the disease only affects males

Correct answer

C. Because the female would need to inherit two mutated X chromosomes

Step-by-step solution

This sex linked recessive disease, which shows its transmission from unaffected carrier female to some of the male progeny has been widely studied. In this disease, a single protein that is a part of the cascade of proteins involved in the clotting of blood is affected. Due to this, in an affected individual a simple cut will result in non-stop bleeding. The heterozygous female (carrier) for haemophilia may transmit the disease to sons. The possibility of a female becoming a haemophilic is extremely rare because mo

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