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NEETZoologyPrinciples of Inheritance and Variation

What is the probability of a heterozygous individual transmitting the sickle-cell trait to their offspring?

Options

  1. A0 percent
  2. B25 percent
  3. C50 percent
  4. D100 percent

Correct answer

C. 50 percent

Step-by-step solution

This is an autosome linked recessive trait that can be transmitted from parents to the offspring when both the partners are carrier for the gene (or heterozygous). The disease is controlled by a single pair of allele, HbA and HbS . Out of the three possible genotypes only homozygous individuals for HbS (HbSHbS ) show the diseased phenotype. Heterozygous (HbAHbS ) individuals appear apparently unaffected but they are carrier of the disease as there is 50 per cent probability of transmission of the mutant gene to the

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