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NEETZoologyPrinciples of Inheritance and Variation

What is the genetic control of β Thalassemia?

Options

  1. AIt is controlled by two genes on chromosome 16
  2. BIt is controlled by a single gene on chromosome 11
  3. CIt is controlled by two genes on chromosome 11
  4. DIt is controlled by a single gene on chromosome 16

Correct answer

B. It is controlled by a single gene on chromosome 11

Step-by-step solution

This causes the formation of abnormal haemoglobin molecules resulting into anaemia which is characteristic of the disease. Thalassemia can be classified according to which chain of the haemoglobin molecule is affected. In α Thalassemia, production of α globin chain is affected while in β Thalassemia, production of β globin chain is affected. α Thalassemia is controlled by two closely linked genes HBA1 and HBA2 on chromosome 16 of each parent and it is observed due to mutation or deletion of one or more of the four

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