Read the following statements regarding genetic blood disorders: (I) Both sickle-cell anaemia and thalassemia are autosomal recessive traits. (II) Thalassemia is a quantitative problem of synthesising too few globin molecules. (III) Sickle-cell anaemia is a qualitative problem of synthesising an incorrectly functioning globin. (IV) Alpha thalassemia is controlled by genes on chromosome 11, while sickle-cell anaemia i

Step-by-step solution

Statement (I) is correct as both sickle-cell anaemia and thalassemia are autosome-linked recessive blood disorders. Statements (II) and (III) are correct. Thalassemia is a quantitative problem of synthesising too few globin molecules, whereas sickle-cell anaemia is a qualitative problem of synthesising an incorrectly functioning globin. Statement (IV) is incorrect because alpha thalassemia is controlled by two closely linked genes (HBA1 and HBA2) on chromosome 16, whereas sickle-cell anaemia (which affects the beta