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NEETZoologyPrinciples of Inheritance and Variation

Read the following statements regarding Mendelian disorders and choose the incorrect statement.

Options

  1. AThalassemia is a qualitative problem of synthesising an incorrectly functioning globin, while sickle-cell anae
  2. BBoth thalassemia and sickle-cell anaemia are autosomal recessive blood disorders.
  3. CThalassemia can be classified into alpha and beta types depending on which chain of the haemoglobin molecule i
  4. DSickle-cell anaemia is caused by the substitution of glutamic acid by valine at the sixth position of the beta

Correct answer

A. Thalassemia is a qualitative problem of synthesising an incorrectly functioning globin, while sickle-cell anae

Step-by-step solution

Thalassemia differs from sickle-cell anaemia in that thalassemia is a quantitative problem of synthesising too few globin molecules, whereas sickle-cell anaemia is a qualitative problem of synthesising an incorrectly functioning globin. The first statement swaps these definitions, making it the incorrect statement. Both disorders are indeed autosomal recessive traits affecting the blood. Thalassemia is classified into alpha and beta types based on the affected haemoglobin chain, and sickle-cell anaemia is caused by

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