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NEETZoologyPrinciples of Inheritance and Variation

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): The possibility of a female becoming haemophilic is extremely rare. Reason (R): For a female to be haemophilic, the mother has to be at least a carrier and the father should be haemophilic. In the light of the above statements, choose the correct answer from the options given below:

Options

  1. ABoth Assertion and Reason are correct but Reason is not the correct explanation of Assertion
  2. BBoth Assertion and Reason are correct and Reason is the correct explanation of Assertion
  3. CAssertion is correct but Reason is incorrect
  4. DAssertion is incorrect but Reason is correct

Correct answer

B. Both Assertion and Reason are correct and Reason is the correct explanation of Assertion

Step-by-step solution

Haemophilia is an X-linked recessive disorder. A female has two X chromosomes (XX), so she must inherit a defective allele from both parents to express the disease. This means her father must be haemophilic ( X^hY ) and her mother must be at least a carrier ( X^hX ) or haemophilic ( X^hX^h ). Because haemophilic males historically became unviable in the later stages of life, this specific parental combination is highly uncommon. Thus, the possibility of a female becoming haemophilic is extremely rare. The Reason is

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