NEETZoologyPrinciples of Inheritance and Variation
Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): The possibility of a female becoming haemophilic is extremely rare. Reason (R): For a female to be haemophilic, the mother has to be at least a carrier and the father should be haemophilic. In the light of the above statements, choose the correct answer from the options given below:
Options
- ABoth Assertion and Reason are correct but Reason is not the correct explanation of Assertion
- BBoth Assertion and Reason are correct and Reason is the correct explanation of Assertion
- CAssertion is correct but Reason is incorrect
- DAssertion is incorrect but Reason is correct
Correct answer
B. Both Assertion and Reason are correct and Reason is the correct explanation of Assertion
Step-by-step solution
Haemophilia is an X-linked recessive disorder. A female has two X chromosomes (XX), so she must inherit a defective allele from both parents to express the disease. This means her father must be haemophilic ( X^hY ) and her mother must be at least a carrier ( X^hX ) or haemophilic ( X^hX^h ). Because haemophilic males historically became unviable in the later stages of life, this specific parental combination is highly uncommon. Thus, the possibility of a female becoming haemophilic is extremely rare. The Reason is