What is responsible for chill and high fever recurring every three to four days in malaria patients?

Step-by-step solution

Malaria is caused by a tiny protozoan named Plasmodium.Malignant malaria, which is the most serious form of malaria, is caused by Plasmodium falciparum.The female Anopheles mosquito is the vector (transmitting agent) in the life cycle of Plasmodium. The sporozoites of Plasmodium are stored in the salivary glands of the mosquito and when the mosquito bites a human, the sporozoites are introduced into their body. The rupture of red blood cells in malaria patients is associated with the release of a toxic substance, h