AIIMS 201926 May
- Exam
- AIIMS
- Year
- 2019
- Date
- 26 May
- Subject
- Zoology
- Chapter
- Chemical Coordination and Integration
AIIMS 2019 · 26 May · Zoology · Chemical Coordination and Integration
Assertion : Insulin forms hormone receptor complex which regulates...
Assertion : Insulin forms hormone receptor complex which regulates the formation of second messenger.
Reason : Insulin is a peptide hormone which can easily pass through cell membrane to interact with intracellular receptors in cell cytoplasm.
Options
- AIf both assertion and reason are true and reason is the correct explanation of assertion.
- BIf both assertion and reason are true but reason is not the correct explanation of assertion.
- CIf assertion is true but reason is false.
- DIf both assertion and reason are false.
Correct answer
C. If assertion is true but reason is false.
Step-by-step solution
Insulin is a peptide hormone produced in the islets of Langerhans in the pancreas. Insulin interacts with membrane bound receptors and does not enter target cell but generates second messenger. Insulin receptors for most cells are less than 100 . Insulin binds to receptors located on plasma membrane to form hormone receptor complex which induces release of GDP from G protein which activates adenyl cyclase that in turn catalysis the formation of cyclic adenosine monophosphate (cAMP) from ATP. The hormone is called first messenger and cAMP is termed as second messenger.