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AIIMS 2012
Exam
AIIMS
Year
2012
Subject
Botany
Chapter
Cell Cycle and Cell Division

AIIMS 2012 · Botany · Cell Cycle and Cell Division

Microtubule depolymerizing drug such as colchicine is expected to

Microtubule depolymerizing drug such as colchicine is expected to

Options

  1. Ainhibit spindle formation during mitosis
  2. Binhibit cytokinesis
  3. Callow mitosis beyond metaphase
  4. Dinduce formation of multiple contractile rings.

Correct answer

A. inhibit spindle formation during mitosis

Step-by-step solution

Colchicine is an alkaloid derived from the autumn crocus, Colchicum autumnale. It inhibits spindle formation in cells during mitosis so that chromosomes cannot separate during anaphase, thus inducing multiple sets of chromosomes. It does not affect cytokinesis.
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