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AIIMS 201827 May
Exam
AIIMS
Year
2018
Date
27 May
Subject
Zoology
Chapter
Organisms and Populations

AIIMS 2018 · 27 May · Zoology · Organisms and Populations

At a particular locus, frequency of allele ' A ' is 0.6 and that of...

At a particular locus, frequency of allele ' AA ' is 0.6 and that of allele ' aa ' is 0.4 . What would be the frequency of heterozygotes in a random mating population at equilibrium?

Options

  1. A0.360.36
  2. B0.160.16
  3. C0.240.24
  4. D0.480.48

Correct answer

D. 0.480.48

Step-by-step solution

In a stable population, for a gene with two alleles, ' A′(dominant)and′a′(recessive),ifthefrequencyof′A' (dominant) and 'a' (recessive), if the frequency of ' A ' is pp and the frequency of ' a\mathrm{a} ' is qq, then the frequencies of the three possible genotypes (AA, Aa and aa) can be expressed by the Hardy-Weinberg equation: p2+2pq+q2=1p^2+2 p q+q^2=1 where p2=p^2= Frequency of AA (homozygous dominant) individuals q2=q^2= Frequency of aa (homozygous recessive) individuals 2pq=2 p q= Frequency of Aa (heterozygous) individuals. So, p=0.6andq=0.4p=0.6 and q=0.4 (given) ∴2pq( frequency of heterozygote )=2×0.6×0.4=0.48.\begin{aligned} \therefore 2 p q(\text{ frequency of heterozygote }) & =2 \times 0.6 \times 0.4 \\ & =0.48 .\end{aligned}
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