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JIPMER 2005
Exam
JIPMER
Year
2005
Subject
Botany
Chapter
Cell Cycle and Cell Division

JIPMER 2005 · Botany · Cell Cycle and Cell Division

Colchicine prevents the mitosis of the cells at which of the...

Colchicine prevents the mitosis of the cells at which of the following stage?

Options

  1. AAnaphase
  2. BMetaphase
  3. CProphase
  4. DInterphase

Correct answer

B. Metaphase

Step-by-step solution

If a cell is treated with drugs such as Colchicine, vincistrine, the assembly of the microtubules is inhibited, while the dis-assembly continues leading to continues disorganization of microtubules. Colchicine is an alkaloid. It can be extracted from corms of plant Colchicum autumnale and C. luteum. Colchicines prevent spindle formation during mitotic metaphase. Thus, it prevents the separation of chromosomes during anaphase stage. Hence, the correct answer is option B.
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