JIPMER2019ZoologyBody Fluids and Circulation
Band 3 protein in RBC has the function of
Options
- Ait mediates the exchange of cellular HCO ₃⁻ with Cl ⁻ in plasma
- Bit is a cytoplasmic protein
- Cit mediates the exchange of cations between cell and plasma
- DBoth (a) and (b)
Correct answer
A. it mediates the exchange of cellular HCO ₃⁻ with Cl ⁻ in plasma
Step-by-step solution
Band 3 protein is a typical polytropic memberane protein that mediates the exchange of cellular bicarbonate ions ( HCO ₃⁻ ) with the chloride ( Cl ⁻ ) ion in plasma, which has been known as the 'chloride shift.' Owing to this, RBC can discriminate the metabolically active cells from inactive cells and deliver oxygen particularly to metabolically active tissue that produce carbon dioxide.