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JIPMER 2018
Exam
JIPMER
Year
2018
Subject
Zoology
Chapter
Molecular Basis of Inheritance

JIPMER 2018 · Zoology · Molecular Basis of Inheritance

Which is present at 5^ end of eukaryotic mRNA?

Which is present at 5′5^{\prime} end of eukaryotic mRNA?

Options

  1. APoly-A tail
  2. BModified C at 5'
  3. C7mG7 mG
  4. DPoly-C

Correct answer

C. 7mG7 mG

Step-by-step solution

At the 5' end of eukaryotic mRNA, 7 mG (7-methyl guanosine) is present. In eukaryotes, primary transcript is often larger than the functional RNAs. Therefore, post-transcription processing is required to convert primary transcript of all types of RNAs into functional RNAs. It is of four types; cleavage, splicing, terminal additional and nucleotide modification. The terminal additions include capping and tailing. In capping, 7 mG is added to 5′5^{\prime} end of mRNA. In tailing, polyadenylation occurs which is addition of poly (A) tail to 3′3^{\prime} end of mRNA.
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