JIPMER 2007
- Exam
- JIPMER
- Year
- 2007
- Subject
- Zoology
- Chapter
- Molecular Basis of Inheritance
JIPMER 2007 · Zoology · Molecular Basis of Inheritance
During transcription holoenzyme RNA polymerase binds to a DNA...
During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called?
Options
- ACAAT box
- BGGTT box
- CAAAT box
- DTATA box
Correct answer
D. TATA box
Step-by-step solution
TATA box is present in eukaryotic promoter region. It has a resemblance with pribnow box of prokaryotes. TATA box was identified by Dr. Hogness and so, it is also called as Hogness box. It is a 7 bp long region located 20 bp upstream to the start point. During the process of transcription the RNA polymerase (a holoenzyme which has a core unit and a sigma factor for proper initiation of transcription) binds to TATA box due to which DNA assumes a saddle like structure at this place.