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JIPMER 2007
Exam
JIPMER
Year
2007
Subject
Zoology
Chapter
Principles of Inheritance and Variation

JIPMER 2007 · Zoology · Principles of Inheritance and Variation

Haemophilia is more commonly seen in human males than in human...

Haemophilia is more commonly seen in human males than in human females becauseHaemophilia is more commonly seen in human males than in human females because

Options

  1. Athis disease is due to an X-linked dominant mutation
  2. Ba greater proportion of girls die in infancy
  3. Cthis disease is due to an X-linked recessive mutation
  4. Dthis disease is due to a Y-linked recessive mutation

Correct answer

C. this disease is due to an X-linked recessive mutation

Step-by-step solution

Haemophilia is more commonly seen in human males than in human females because Haemophilia, a hereditary (recessive X-linked) disease is caused due to fault in genes, which controlling the factor VIII and IX, located on X-chromosome. The male carries only one X-chromosome, his other sex chromosome, which carries no genes for blood clotting, so the condition is usually seen only in males where only one faulty chromosome is needed. While a female with one faulty X-chromosome will be carrier. So, in females two faulty X-chromosomes are needed to cause the disease.
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