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MHT CET Medical202624 April 2026Morning ShiftBiologyBiomolecules (B)Actual

Which one of the following is the activator for enzyme Pyruvate Kinase?

Options

  1. AZn ⁺⁺
  2. BMg ⁺⁺
  3. CCa ⁺⁺
  4. DMn ⁺⁺

Correct answer

B. Mg ⁺⁺

Step-by-step solution

Pyruvate kinase is an enzyme that catalyzes the final step of glycolysis, converting phosphoenolpyruvate to pyruvate with the generation of ATP. Like most kinase enzymes involved in phosphate transfer reactions, it requires a divalent metal cation as a cofactor for its catalytic activity. The magnesium ion ( Mg⁺⁺ ) acts as the primary physiological activator for the enzyme pyruvate kinase. Answer: Mg ⁺⁺

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