MHT CET Medical202622 April 2026Morning ShiftBiologyBiomolecules (B)Actual
Which one of the following statements is INCORRECT based on the above graph showing the rate of enzyme action?
Options
- AK _m or Michaelis-Menten constant is the substrate concentration to produce half of the maximum velocity in an
- BIt shows that half of the enzyme molecules are bound with substrate molecules when substate concentration equa
- CA high K _m value indicates a strong affinity between enzyme and substrate.
- DThe maximum rate of an enzyme reaction is directly proportional to the concentration of enzymes.
Correct answer
C. A high K _m value indicates a strong affinity between enzyme and substrate.
Step-by-step solution
The Michaelis-Menten constant ( K_m ) is defined as the substrate concentration at which the reaction rate is half of its maximum velocity ( V_ max /2 ). This directly supports statement (1). At K_m , the reaction rate is V_ max /2 . This means that exactly half of the active sites on the enzyme molecules are occupied by substrate molecules. This supports statement (2). The maximum rate of an enzyme-catalyzed reaction ( V_ max ) is directly proportional to the total concentration of the enzyme present ( V_ max = k_