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MHT CET Medical202621 April 2026Evening ShiftBiologyBiomolecules (B)Actual

Match Column I with Column II Column I (Scientist) Column II (Discoveries) (A) Edward Buchner (I). Lock and Key hypothesis (B) Emil Fischner (II). Induced Fit theory (C) Koshland (III). K_m and Vmax concept (D) Michaelis -Menten (IV). Yeast fermentation Choose the correct answer from the options given below:

Options

  1. A(A) - (IV), (B) - (I), (C) - (II), (D) - (III)
  2. B(A) - (III), (B) - (II), (C) - (I), (D) - (IV)
  3. C(A) - (II), (B) - (III), (C) - (IV), (D) - (I)
  4. D(A) - (I), (B) - (IV), (C) - (III), (D) - (II)

Correct answer

A. (A) - (IV), (B) - (I), (C) - (II), (D) - (III)

Step-by-step solution

Edward Buchner discovered that cell-free extracts of yeast could ferment sugar, leading to the discovery of the enzyme complex zymase. Thus, (A) matches (IV). Emil Fischer proposed the Lock and Key hypothesis in 1894 to explain the specificity of enzymes. Thus, (B) matches (I). Daniel Koshland proposed the Induced Fit theory in 1958, which states that the binding of a substrate induces a conformational change in the active site of the enzyme. Thus, (C) matches (II). Leonor Michaelis and Maud Menten developed the Mi

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