MHT CET Medical202623 April 2026Evening ShiftBiologyBreathing and Exchange of GasesActual
Which of the following is NOT directly related to chloride shift?
Options
- ACarbonic anhydrase activity
- BBohr effect
- CHaldane effect
- DBicarbonate transport
Correct answer
B. Bohr effect
Step-by-step solution
Chloride shift, also known as the Hamburger phenomenon, is the process where bicarbonate ions ( HCO₃^- ) diffuse out of red blood cells (RBCs) into the plasma, and to maintain electrical neutrality, chloride ions ( Cl^- ) diffuse from the plasma into the RBCs. This process is a crucial part of carbon dioxide ( CO₂ ) transport in the blood. Carbonic anhydrase activity is directly related because it catalyzes the hydration of CO₂ to form carbonic acid ( H₂CO₃ ), which then dissociates into H^+ and HCO₃^- . Bicarbonat