MHT CET Medical202622 April 2026Morning ShiftBiologyHuman Health and DiseasesActual
The antigen binding site of the antibody is formed of ______.
Options
- Avariable and constant regions of light chain
- Bvariable and constant regions of heavy chain
- Cvariable regions of both light and heavy chains
- Dconstant regions of both light and heavy chains
Correct answer
C. variable regions of both light and heavy chains
Step-by-step solution
An antibody molecule is composed of four polypeptide chains: two identical light chains and two identical heavy chains. Each chain consists of a variable region at its N-terminal end and a constant region at its C-terminal end. The variable regions of both the light and heavy chains come together to form the antigen binding site (paratope), which is highly specific for a particular antigen. Therefore, the antigen binding site of the antibody is formed of the variable regions of both light and heavy chains. Answer: