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MHT CET Medical202625 April 2026Evening ShiftBiologyPrinciples of Inheritance and VariationActual

Extra copy of 21st chromosome causes _________ in human.

Options

  1. ATurner's syndrome
  2. BKlinefelter's syndrome
  3. CThalassemia
  4. DDown's syndrome

Correct answer

D. Down's syndrome

Step-by-step solution

Down's syndrome is a genetic disorder caused by the presence of an additional copy of chromosome 21 , also known as Trisomy 21 . Turner's syndrome is caused by the absence of one of the X chromosomes, resulting in a 45 , X 0 karyotype. Klinefelter's syndrome is caused by the presence of an additional X chromosome, resulting in a 47 , XXY karyotype. Thalassemia is an autosomal recessive blood disorder. Therefore, an extra copy of the 21 st chromosome causes Down's syndrome. Answer: Down's syndrome

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