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MHT CET Medical202624 April 2026Evening ShiftBiologyRespiration in PlantsActual

In Krebs' cycle, GTP is produced during the conversion of ___.

Options

  1. A-ketoglutarate to succinyl CoA.
  2. Bfumarate to malate.
  3. Csuccinate to fumarate.
  4. Dsuccinyl CoA to succinic acid.

Correct answer

D. succinyl CoA to succinic acid.

Step-by-step solution

In the Krebs cycle, the conversion of succinyl CoA to succinic acid is catalyzed by the enzyme succinyl-CoA synthetase. During this reaction, the cleavage of the high-energy thioester bond of succinyl CoA releases energy, which is used to phosphorylate a molecule of GDP to GTP. This process is an example of substrate-level phosphorylation. The GTP produced can subsequently transfer its terminal phosphate group to ADP to form ATP. Therefore, GTP is produced during the conversion of succinyl CoA to succinic acid. Ans

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