MHT CET Medical202623 April 2026Evening ShiftBiologyRespiration in PlantsActual
In glycolysis, which enzyme requires Zn ²⁺ as cofactor?
Options
- AHexokinase
- BPhosphofructokinase
- CAldolase
- DGlyceraldehyde phosphate dehydrogenase
Correct answer
C. Aldolase
Step-by-step solution
In the process of glycolysis, specific enzymes require metal ions or coenzymes as cofactors for their catalytic activity. Hexokinase and Phosphofructokinase are kinase enzymes that catalyze the transfer of phosphate groups from ATP. They typically require Mg²⁺ as a cofactor to stabilize the negative charges of ATP. Glyceraldehyde phosphate dehydrogenase is an oxidoreductase enzyme that utilizes the coenzyme NAD^+ to catalyze its reaction and does not require a metal ion cofactor. Aldolase, specifically Class II ald