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NEET 2017
Exam
NEET
Year
2017
Subject
Botany
Chapter
Cell Cycle and Cell Division

NEET 2017 · Botany · Cell Cycle and Cell Division

Anaphase promoting complex (APC) is a protein degradation machinery...

Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?

Options

  1. AChromosomes will not condense
  2. BChromosomes will be fragmented
  3. CChromosomes will not segregate
  4. DRecombination of chromosome arms will occur

Correct answer

C. Chromosomes will not segregate

Step-by-step solution

Anaphase Promoting Complex (APC) is a protein necessary for the separation of daughter chromosomes during anaphase.

APC degenerates proteins binding the two chromatids in the region of the centromere. As a result, the centromere of each chromosome divides.

If APC is defective, then the chromosomes will fail to segregate during anaphase.

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